The Arctic is an integral part of the larger Earth system where multiple interactions unite its natural and human components. As is amply demonstrated in each annual installment of the Arctic Report Card, the domain is collectively experiencing rapid and amplified signatures of global climate change. At the same time, the Arctic system’s response to this broader forcing has, itself, become a central research topic, given its potential role as a critical throttle on future planetary dynamics (NRC 2013, 2014). Changes are already impacting life systems, cultures and economic prosperity and continued change is expected to bear major implications far outside the region (ACIA 2005, AMAP 2012, IPCC 2013, Cohen et al. 2014). Ongoing assessments of how the system is wired-together and how sensitive its environment is to change suggest that there are important interconnections and possible feedbacks but these remain highly uncertain (Francis et al. 2009a; Hinzman et al. 2013). We have entered an era when environmental management, traditionally local in scope, must confront regional, whole biome, and pan-Arctic challenges but also requires policy development that crosses scales and boundaries from villages to international partnerships.